

12 Department of Electronic, Information and Bioengineering, Politecnico di Milano, Milan, Lombardia, Italy.Chan School of Public Health, Boston, MA, USA. 11 Department of Biostatistics, Harvard T.H.10 Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.9 Laboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA, USA.8 Department of Oncology, University of Turin, Turin, Piemonte, Italy.Luigi Gonzaga, Orbassano, Piemonte, Italy. 7 Department of Anesthesia and Critical Care, Azienda Ospedaliero-Universitaria S.Martino Hospital, Belluno, Veneto, Italy. 6 Operative Unit ofAnesthesia and Intensive Care Unit, S.5 Palliative and Advanced Illness Research (PAIR) Center and Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

